Patient panel
All
High flare risk
Dysautonomia
CKD
EDS / connective tissue
Diabetes
Fibromyalgia
Lupus / systemic
Julie Founder
High risk
CKD · dysautonomia pattern · chronic pain
Layla Nguyen
Moderate
ADHD · IBS · possible EDS & POTS cluster
John Doe
Low
POTS · migraine · suspected MCAS
Panel insights
Dysautonomia signature
38%
of active patients
CKD overlap
12
patients with renal flags
Suspected autoimmune
19
meeting lupus-like pattern
Julie Founder · 44
CKD · chronic pain · orthostatic intolerance · suspected autoimmune overlap
Flare risk (Owlfred)
High
Autonomic / Dysautonomia
High
Positional tachycardia, presyncope, heat intolerance, and “adrenaline surge”
episodes clustered around flare days.
Connective tissue / EDS
Moderate
Joint hypermobility with recurrent sprains, soft-tissue pain, bruising, and
slow recovery after minor strain.
Metabolic / Diabetes pattern
Moderate
Episodes of intense thirst, frequent urination, brain fog, and fatigue
mapping to elevated glucose windows.
Renal / CKD pattern
High
Tea colored or foamy urine, ankle/hand swelling, and fatigue aligned with
reduced eGFR or proteinuria events.
Pain & fatigue / Fibromyalgia
High
Widespread muscular and fascial pain, tender points, non-restorative sleep,
and sensory overload in multi-system flares.
Immune & systemic / Lupus pattern
Moderate
Photosensitive rash, mucosal ulcers, chest tightness, and low-grade fevers
clustered near complement and renal shifts.
Pattern matches are based on longitudinal symptoms, vitals, and labs. Owlfred
does not make a diagnosis and is intended to support, not replace, clinical judgement.
Recent labs
| eGFR | 52 ml/min | Stable CKD stage 3 pattern. |
| C3 complement | 201 mg/dL | Persistently high; renal/inflammatory overlap. |
| Urinalysis | Trace blood, no protein | Matches dark urine days. |
| Vitamin D | 18.9 ng/mL | Chronic deficiency. |
| Glucose trend | 90–128 mg/dL | Spikes on high-stress / poor sleep days. |
Suggested next steps
- Review dysautonomia and CKD clusters across last three flares.
- Consider updated renal + autoimmune panel and autonomic testing.
- Reinforce pre-flare protocol (hydration, salt, pacing, reduced exertion).

